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Researchers must navigate these requirements while maintaining scientific rigor and participant safety

Epigenetic regulation of CSCs Epigenetic mechanismsincluding DNA methylation, histone modification, and chromatin remodelingplay pivotal roles in regulating CSC properties such as self-renewal, plasticity, differentiation, and therapeutic resistance

Our study confirmed that SFN can be effective against cutaneous inflammation in an IMQ-induced psoriatic mouse model, consistent with previous findings of its therapeutic effects in chronic inflammatory diseases such as inflammatory bowel disease, respiratory diseases, and rheumatoid arthritis [35]